发明名称 2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS
摘要 This invention relates to compounds of the formula wherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.
申请公布号 KR20130100241(A) 申请公布日期 2013.09.10
申请号 KR20127031991 申请日期 2011.05.03
申请人 F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A. 发明人 BANNER DAVID;GUBA WOLFGANG;HILPERT HANS;HUMM ROLAND;MAUSER HARALD;MAYWEG ALEXANDER V.;NARQUIZIAN ROBERT;POWER EOIN;ROGERS EVANS MARK;ROMBACH DIDIER;WOLTERING THOMAS;WOSTL WOLFGANG
分类号 C07D413/12;A61K31/553;A61P9/00;A61P25/00 主分类号 C07D413/12
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