发明名称 |
2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS |
摘要 |
This invention relates to compounds of the formula wherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.
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申请公布号 |
KR20130100241(A) |
申请公布日期 |
2013.09.10 |
申请号 |
KR20127031991 |
申请日期 |
2011.05.03 |
申请人 |
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A. |
发明人 |
BANNER DAVID;GUBA WOLFGANG;HILPERT HANS;HUMM ROLAND;MAUSER HARALD;MAYWEG ALEXANDER V.;NARQUIZIAN ROBERT;POWER EOIN;ROGERS EVANS MARK;ROMBACH DIDIER;WOLTERING THOMAS;WOSTL WOLFGANG |
分类号 |
C07D413/12;A61K31/553;A61P9/00;A61P25/00 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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