Corynebacteria strain for enhancement of 5'-guanosine monophosphate productivity and a method of producing 5'-guanosine monophosphate using the same

摘要

Disclosed is a method of producing 5'-guanosine monophosphate using a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type, thereby showing improved ATP productivity. Also, a novel microorganism is disclosed. The method comprises: culturing the corynebacteria strain which is enhanced in malate dehydrogenase activity over the endogenous activity, thus producing ATP in high yield; producing XMP in the culture; adding to the culture an enzyme or microorganism having XMP amination activity; and obtaining GMP from the culture.