METHOD FOR PREPARING DRUG MICROCAPSULES OF CEPHALOSPORIN IN KONJAC GUM IN CHLOROFORM

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to microcapsulation of drug preparations of cephalosporins referred to ?-lactam antibiotics in konjac gum by physical-chemical precipitation in a non-solvent. Konjac gum is used as a microcapsule membrane. The microcapsules are prepared by physical-chemical precipitation in the non-solvent with using two precipitation agents - carbinol and chloroform. The process of microcapsules is carried out at 25°C with no special equipment required.EFFECT: method according to the invention provides simplifying and accelerating the process of microcapsules of drug preparations of cephalosporins, and reducing losses (higher weight yield).4 ex