发明名称 Broad spectrum gram-positive antimicrobials and anthelmintics with efficacy against drug-resistant strains and Mycobacterium species
摘要 The present invention provides compounds and methods of using of the compounds as anti-infective and anthelminitc agents. In a preferred embodiment, the present invention provides the following compound of Formula III: wherein: R1 is not H when R2 is H and R2 is not H when R1 is H, further wherein R1 is OH or CH(2n+1)O, wherein n is 1-10; R2 is OH or CH(2n+1)O, where n is 1-10; W is alkyl, phenyl, halophenyl, pyridyl, piperidyl, or a substituted or unsubstituted aryl group, including unsubstituted and substituted aromatic heterocycles; and L is an optional linker or linking group selected from O, S, NH, CF2, or CH2, and x=0 or 1, i.e., if x=0, no linking group is present and when x=0, W is not phenyl.
申请公布号 US8530512(B2) 申请公布日期 2013.09.10
申请号 US20100973078 申请日期 2010.12.20
申请人 MONTE AARON P.;KABIR M. SHAHJAHAN;ROTT MARC A.;SCHWAN WILLIAM R.;COOK, III JAMES M.;MISKOWSKI JENNIFER A.;VERMA RANJIT;DEFOE LEAH 发明人 MONTE AARON P.;KABIR M. SHAHJAHAN;ROTT MARC A.;SCHWAN WILLIAM R.;COOK, III JAMES M.;MISKOWSKI JENNIFER A.;VERMA RANJIT;DEFOE LEAH
分类号 A61K31/38;A61K31/34;A61K31/404 主分类号 A61K31/38
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