| 发明名称 |
Modulation of apolipoprotein C-III expression |
| 摘要 |
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided. |
| 申请公布号 |
US8530439(B2) |
申请公布日期 |
2013.09.10 |
| 申请号 |
US20100781479 |
申请日期 |
2010.05.17 |
| 申请人 |
CROOKE ROSANNE M.;GRAHAM MARK J.;LEMONIDIS KRISTINA M.;DOBIE KENNETH W.;ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE ROSANNE M.;GRAHAM MARK J.;LEMONIDIS KRISTINA M.;DOBIE KENNETH W. |
| 分类号 |
A61K38/00;A61K48/00;C07H21/02;C07H21/04;C12N15/113 |
主分类号 |
A61K38/00 |
| 代理机构 |
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