发明名称 |
Electrochemical methods of detecting cancer with 4-aminophenyl phosphate |
摘要 |
A method of detecting cancer cells is disclosed. The method comprises (a) contacting the cell which is suspicious of a cancerous or undifferentiated phenotype with 4-aminophenyl phosphate (p-APP) under conditions wherein alkaline phosphatase of the cell catalyzes a reaction of the cell with the p-APP, so as to generate a product capable of producing an electrical signal; and (b) measuring a level of the electrical signal, wherein a difference in a level of the electrical signal compared to a predetermined threshold is indicative of a cancer cell.
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申请公布号 |
US8530179(B2) |
申请公布日期 |
2013.09.10 |
申请号 |
US201213551642 |
申请日期 |
2012.07.18 |
申请人 |
RISHPON JUDITH;POPOVTZER RACHELA;SHACHAM-DIAMAND YOSI;NEUFELD TOVA;VERNICK SEFI;RAMOT AT TEL-AVIV UNIVERSITY LTD |
发明人 |
RISHPON JUDITH;POPOVTZER RACHELA;SHACHAM-DIAMAND YOSI;NEUFELD TOVA;VERNICK SEFI |
分类号 |
C12Q1/42 |
主分类号 |
C12Q1/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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