发明名称 D-AMINO ACID PEPTIDES
摘要 The present invention provides compounds of the formula X-R1-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)-R3(Y)-NR4R5; or R1(X)-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)-R3(Y)-NR4R5, in which X is a hard acid cation chelator, a soft acid cation chelator or Ac-, R1, R2 and R3 are independently selected from a covalent bond or one or more D-amino acids that can be the same or different, Y is a hard acid cation chelator, a soft acid cation chelator or absent, Z is a hard acid cation chelator, a soft acid cation chelator or absent, and A and B are haptens or hard acid cation chelators and can be the same or different, and R4 and R5 are independently selected from the group consisting of hard acid cation chelators, soft acid cation chelators, enzymes, therapeutic agents, diagnostic agents and H. The present invention also provides methods of using these compounds and kits containing the compounds.
申请公布号 CA2529027(C) 申请公布日期 2013.09.10
申请号 CA20042529027 申请日期 2004.06.14
申请人 IMMUNOMEDICS, INC. 发明人 MCBRIDE, WILLIAM J.;GOLDENBERG, DAVID M.
分类号 C07K7/06;A61K31/4745;A61K31/704;A61K38/00;A61K38/46;A61K45/00;A61K47/42;A61K49/00;A61K51/10;C07K5/10;C12Q1/02;G01N33/569 主分类号 C07K7/06
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