发明名称 |
INVERSE PATTERNING PROCESS FOR THREE-DIMENSIONAL MULTI-COMPARTMENTAL MICRO-ORGANIZATION OF MULTIPLE CELL TYPES |
摘要 |
The invention features an "inverse patterning" or "Intaglio-Void/Embed-Relief Topographic (In VERT) molding" manufacturing process for generating high-resolution three-dimensional (3D) multi-cellular microstructures in distinct cellular compartments of a single hydrogel. The platform has general utility in the development of engineered tissues for human therapies, drug testing, and disease models. Additionally, the platform can serve as a model system for studying 3D cell-cell interactions in fields as diverse as stem cell biology to the development of cancer therapeutics. |
申请公布号 |
WO2013130823(A1) |
申请公布日期 |
2013.09.06 |
申请号 |
WO2013US28345 |
申请日期 |
2013.02.28 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
BHATIA, SANGEETA, N.;STEVENS, KELLY, R. |
分类号 |
C12N5/00 |
主分类号 |
C12N5/00 |
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