<p>The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.</p>
申请公布号
WO2013127841(A1)
申请公布日期
2013.09.06
申请号
WO2013EP53916
申请日期
2013.02.27
申请人
F. HOFFMANN-LA ROCHE AG;FIROOZNIA, FARIBORZ;LIN, TAI-AN;MERTZ, ERIC;SIDDURI, ACHYUTHARAO;SO, SUNG-SAU;TILLEY, JEFFERSON WRIGHT
发明人
FIROOZNIA, FARIBORZ;LIN, TAI-AN;MERTZ, ERIC;SIDDURI, ACHYUTHARAO;SO, SUNG-SAU;TILLEY, JEFFERSON WRIGHT