METHODS FOR SCREENING VOLTAGE GATED PROTEINS

摘要

In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage gated ion channel. In certain embodiments, the voltage gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.