TRUNCATED LYSOSOMAL ACID LIPASE

摘要

Recombinant human lysosomal acid lipase (rhLAL) containing an N -terminal truncation, a composition of truncated recombinant human LAL (TLAL), an isolated mixture comprising TLAL and at least one other form of rhLAL are disclosed. A method of purifying TLAL from a mixture of LAL proteins, pharmaceutical compositions comprising TLAL and methods of producing TLAL are further disclosed.