METHOD FOR DESIGNATING DISEASE RELATING TO AMOUNT OF TDP-43 EXISTING IN CELLS

摘要

The present invention addresses the problem of developing and providing a method for designating a disease that relates to the amount of TDP-43 existing in cells and a method for producing a TDP-43 binding inhibitor. By collecting cells from a subject and measuring the existing amount of a test substance in the cells, the binding amount of the test substance to TDP-43 in the cells, etc., whether or not the subject suffers from a disease that relates to the amount of TDP-43 existing in cells is designated. By adding a medicine candidate, a medicine capable of significantly reducing the binding of the test substance to TDP-43 is produced.