发明名称 |
CELL PENETRATING PEPTIDE DERIVED FROM HUMAN LPIN3 PROTEIN AND CARGO DELIVERY SYSTEM USING THE SAME |
摘要 |
PURPOSE: A cell penetrating domain is provided to introduce a cargo protein into cells with high efficiency and to prevent immune response problems, thereby being used as a signal sequence for delivering various polymeric substances into cells. CONSTITUTION: A cell penetrating domain contains a nuclear localization signal sequence of human LPIN3 protein. A recombinant cargo with improved cell membrane permeability contains the cell penetrating domain and a cargo which is fused at N-terminal or C-terminal of the cell penetrating domain. A method for delivering the cargo into cells comprises the steps of: preparing the recombinant cargo; and making the recombinant cargo touch cells. |
申请公布号 |
KR20130098839(A) |
申请公布日期 |
2013.09.05 |
申请号 |
KR20120152966 |
申请日期 |
2012.12.26 |
申请人 |
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) |
发明人 |
CHOI, JE MIN;LIM, SANG HO;KIM, YEON HO |
分类号 |
C07K14/47;C12N15/63 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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