PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF HEPATIC FIBROSIS AND LIVER CIRRHOSIS COMPRISING RAMALIN
摘要
PURPOSE: A pharmaceutical composition for preventing or treating hepatic fibrosis or liver cirrhosis is provided to effectively suppress hepatic fibrosis without cytotoxicity to normal hepatocytes using ramalin, thereby effectively preventing or treating hepatic fibrosis and liver cirrhosis. CONSTITUTION: A pharmaceutical composition for preventing or treating hepatic fibrosis or liver cirrhosis contains a compound of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient. A functional food for preventing or treating hepatic fibrosis or liver cirrhosis contains the compound or a sitologically acceptable salt thereof as an active ingredient. A pharmaceutical composition for preventing or treating hepatic fibrosis or liver cirrhosis contains a Ramalina terebrata extract containing the compound of chemical formula 1 as an active ingredient.
申请公布号
KR20130098745(A)
申请公布日期
2013.09.05
申请号
KR20120020515
申请日期
2012.02.28
申请人
KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY
发明人
YIM, JOUNG HAN;KIM, IL CHAN;KIM, DOC KYU;HAN, SE JONG;LEE, HYOUNG SEOK;HARI DATTA BHATTARAI;YANG, SU GEUN;LEE, DON HANG