发明名称 SUBSTITUTED AMIDE COMPOUND
摘要 A substituted amide compound is useful as an active ingredient of a pharmaceutical composition, in particular a pharmaceutical composition for treating diseases caused by lysophosphatidic acid (LPA). The compound is of a formula: In this formula, A is an optionally substituted aryl, etc.; B is an optionally substituted 5-membered aromatic hetero ring group; X is a single bond or -(CRX1RX2)n-; n is 1, 2, 3, or 4; RX1 and RX2 are hydrogen, etc.; Y1 to Y5 are each CRY or N; each RY is hydrogen, etc.; R1 and R2 are hydrogen, etc.; m is 1, 2, or 3; R3 is hydrogen, etc.; and R4 is an optically substituted lower alkyl, etc.
申请公布号 US2013231320(A1) 申请公布日期 2013.09.05
申请号 US201313783858 申请日期 2013.03.04
申请人 ASTELLAS PHARMA INC. 发明人 KAWAMINAMI EIJI;TAKAHASHI TATSUHISA;KANAYAMA TAKATOSHI;FUKUDA YUTA;KAIZAWA HIROYUKI;KONDOH YUTAKA;SEO RYUSHI;KURAMOTO KAZUYUKI;TAKE KAZUHIKO;SAKAMOTO KAZUYUKI
分类号 A61K31/426;A61K31/427 主分类号 A61K31/426
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