发明名称 |
PREPARATION METHOD FOR CASPOFUNGIN |
摘要 |
Disclosed is a preparation method for caspofungin, comprising the steps: (a) a compound as represented in Formula 2 and a strong leaving group 5 are mixed to obtain a compound as represented in Formula 3; (b) the compound as represented in Formula 3 and ethylenediamine are mixed to obtain a compound as represented in Formula 4; and, (c) the compound as represented in Formula 4 is mixed with a hydroxyl protection agent, and then a borane complex is mixed in to obtain a compound as represented in Formula 1. |
申请公布号 |
US2013231457(A1) |
申请公布日期 |
2013.09.05 |
申请号 |
US201113884686 |
申请日期 |
2011.11.10 |
申请人 |
HE BINGMING;LI MING;TANG ZHIJUN;JI XIAOMING;SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD. |
发明人 |
HE BINGMING;LI MING;TANG ZHIJUN;JI XIAOMING |
分类号 |
C07K7/64 |
主分类号 |
C07K7/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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