发明名称 Procedimiento para la preparación de valsartan
摘要 The present invention relates to a process for preparing valsartan from a compound of general formula (I), wherein R is cumyl, trityl or t-butyl. The process comprises a first step, wherein the protective group is eliminated and thereafter the oxazolidinone ring is opened by catalytic hydrogenationin the presence of an organic base. Finally, Valsartanor a pharmaceutically acceptable salt thereofis isolated.
申请公布号 ES2421641(T3) 申请公布日期 2013.09.04
申请号 ES20080750212T 申请日期 2008.05.08
申请人 CHEMO IBERICA, S.A. 发明人 COSME GOMEZ, ANTONIO;PALOMO NICOLAU, FRANCISCO EUGENIO
分类号 C07D257/04;C07D413/10 主分类号 C07D257/04
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