发明名称 |
NEW MARKER OF BREAST TUMORS FROM THE LUMINAL-B SYBTYPE |
摘要 |
<p>An in vitro method for diagnosing a breast cancer from the luminal-B subtype in a female, includes the steps of analyzing a biological sample from the female by (i) determining the copies number of the ZNF703 gene, and/or (ii) determining the expression of the ZNF703 gene, wherein an increased copies number and/or an over-expression of the ZNF703 gene is indicative of a luminal B tumor; to a kit for diagnosing a breast cancer from the luminal-B subtype in a female including at least one nucleic acid probe or oligonucleotide or at least one antibody, which can be used in a method as defined previously, for determining the copies number of the ZNF703 gene, and/or determining the expression of the ZNF703 gene; and to the use of such a kit.</p> |
申请公布号 |
EP2633070(A1) |
申请公布日期 |
2013.09.04 |
申请号 |
EP20110779582 |
申请日期 |
2011.10.28 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE D'AIX MARSEILLE;INSTITUT PAOLI-CALMETTES |
发明人 |
BIRNBAUM, DANIEL;CHAFFANET, MAX;GINESTIER, CHRISTOPHE;ADELAIDE, JOSE;SIRCOULOMB, FABRICE |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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