| 发明名称 |
HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS |
| 摘要 |
<p>Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both.</p> |
| 申请公布号 |
EP2057139(B1) |
申请公布日期 |
2013.09.04 |
| 申请号 |
EP20070763931 |
申请日期 |
2007.07.18 |
| 申请人 |
ANTIBE THERAPEUTICS INC. |
发明人 |
WALLACE, JOHN, L.;CIRINO, GIUSEPPE;SANTAGADA, VINCENZO;CALIENDO, GIUSEPPE |
| 分类号 |
C07C219/14;A61K31/385;A61P29/00;C07C327/48;C07D209/18;C07D209/32;C07D309/30;C07D339/04;C07D409/12 |
主分类号 |
C07C219/14 |
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