发明名称 |
COMPOSITIONS AND METHODS FOR TARGETING TYPE 1 INTERFERON PRODUCING CELLS |
摘要 |
The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor a (IL-3Ra) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds. |
申请公布号 |
EP2536430(A4) |
申请公布日期 |
2013.09.04 |
申请号 |
EP20110744183 |
申请日期 |
2011.02.17 |
申请人 |
CSL LIMITED |
发明人 |
VAIRO, GINO, LUIGI;NASH, ANDREW;MARASKOVSKY, EUGENE;WILSON, NICK;BUSFIELD, SAMANTHA;PANOUSIS, CON |
分类号 |
C07K16/28;A61K39/395;A61P35/02;A61P37/06 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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