发明名称 HIV INTEGRASE INHIBITORS
摘要 <p>Tricyclic compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: (I), wherein R1A, R1B, R1C, R2A, R2B, R3A, R3B, R4, R5 and R6 are defined herein. The compounds are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.</p>
申请公布号 EP2632454(A1) 申请公布日期 2013.09.04
申请号 EP20110836929 申请日期 2011.10.25
申请人 MERCK SHARP & DOHME CORP.;MERCK CANADA INC. 发明人 BARBE, GUILLAUME;NGUYEN, NATALIE, N., M.;BLOUIN, MARC;GAREAU, YVES;POWELL, DAVID, A.;COTE, BERNARD;HUMPHREY, GUY ROLAND;KUETHE, JEFFREY THOMAS;CHILDERS, KARLA GLASER;FARAND, JULIE;TREPANIER, VICENT HECTOR EMILE;LARIVEE, ALEXANDRE;RADA, VANESSA LOUISE;EMBREY, MARK, W.;STEELE, THOMAS, G.;SISKO, JOHN, T.;BENNETT, DAVID JONATHAN;RAHEEM, IZZAT TIEDJE;SCHREIER, JOHN DAVID;HARTINGH, TIMOTHY JOHN;SHIPE,WILLIAM, D.;BUNDA, JAIME LYNN
分类号 A61K31/235;A61K31/66 主分类号 A61K31/235
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