发明名称 |
OCULAR DRUG DELIVERY DEVICES |
摘要 |
A method of forming an ocular delivery device includes exposing a solid, shaped cellulose polymer to a solution including an active pharmaceutical ingredient (API) and a solvent capable of solubilizing the API, wherein the polymer absorbs at least a portion of the solution, including the API and solvent. The method may further include removing at least a portion of the absorbed solvent from the polymer by allowing the absorbed solvent to evaporate from the polymer or by drying the polymer. A variety of cellulose polymers may be used, including hydroxypropyl cellulose. A variety of APIs may be used, including Cyclosporine, Tobramycin and Vancomycin. Ocular delivery devices prepared by the methods may be used to treat a variety of eye disorders. |
申请公布号 |
EP2493459(A4) |
申请公布日期 |
2013.09.04 |
申请号 |
EP20100827563 |
申请日期 |
2010.10.29 |
申请人 |
ATON PHARMA, INC.;LOUISIANA STATE UNIVERSITY AGRICULTURAL AND MECHANICAL COLLEGE |
发明人 |
JACOB, JEAN THERESA;HALLORAN, KEVIN JOHN;MCKEE, YURI |
分类号 |
A61K9/50;C08L1/26 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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