发明名称 |
Proton acceptor iminium/carbocation-type coupling agents |
摘要 |
Novel iminium-type coupling agents containing proton acceptors in their iminium moiety, which can be used beneficially as coupling agents in various chemical polypeptide and/or polynucleotide syntheses, and are particularly useful as yield enhancing and racemization suppressing coupling agents for use in peptide syntheses, are disclosed. Further disclosed are a process of preparing such iminium-type coupling agents and their use in the preparation of polypeptides and/or polynucleotides.
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申请公布号 |
US8524898(B2) |
申请公布日期 |
2013.09.03 |
申请号 |
US20080451496 |
申请日期 |
2008.05.15 |
申请人 |
ALBERICIO FERNANDO;EL-FAHAM AYMAN;LUXEMBOURG YOAV;EWENSON ARIEL;LUXEMBOURG BIO TECHNOLOGIES LTD. |
发明人 |
ALBERICIO FERNANDO;EL-FAHAM AYMAN;LUXEMBOURG YOAV;EWENSON ARIEL |
分类号 |
C07D295/00 |
主分类号 |
C07D295/00 |
代理机构 |
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