发明名称 |
STRATIFICATION OF CANCER PATIENTS FOR SUSCEPTIBILITY TO THERAPY WITH PTK2 INHIBITORS |
摘要 |
A method for determining whether a cancer patient is susceptible to treatment with a protein tyrosine kinase 2 (PTK2) inhibitor, comprising detecting the expression of the E-cadherin protein in a cancer sample of said cancer patient, wherein an E-cadherin protein immunoreactivity score (IRS) of 0-2 indicates that the cancer patient is susceptible to treatment with a PTK2 inhibitor. The invention further encompasses treatment of a patient with a protein tyrosine kinase 2 (PTK2) inhibitor if it has been so determined that said patient is susceptible to such treatment.
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申请公布号 |
KR20130097196(A) |
申请公布日期 |
2013.09.02 |
申请号 |
KR20137007786 |
申请日期 |
2011.09.26 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
ADOLF GUENTHER;GARIN CHESA PILAR;HIRT ULRICH |
分类号 |
G01N33/574;G01N33/53;G01N33/68 |
主分类号 |
G01N33/574 |
代理机构 |
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地址 |
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