发明名称 |
ANVENDELSE AF THIOFLAVIN RADIOMARKEREDE DERIVATER I AMYLOID BILLEDDANNELSE TIL VURDERING AF ANTI-AMYLOIDE TERAPIER |
摘要 |
The present method for determining the efficacy of therapy in the treatment of amyloidosis involves administering to a patient in need thereof a compound of formula (I) or Formula (II) or structures 1-45 and imaging the patient. After said imaging, at least one anti-amyloid agent is administered to said patient. Then, an effective amount of a compound of formula (I) or Formula (II) or structures 1-45 is administered to the patient and the patient is imaged again. Finally, baseline levels of amyloid deposition in the patient before treatment with the anti-amyloid agent are compared with levels of amyloid deposition in the patient following treatment with the anti-amyloid agent. |
申请公布号 |
DK1771208(T3) |
申请公布日期 |
2013.09.02 |
申请号 |
DK20050787557T |
申请日期 |
2005.07.01 |
申请人 |
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
KLUNK, WILLIAM E.;MATHIS, CHESTER, A., JR |
分类号 |
A61K51/04;A61P25/28 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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