发明名称 BENZAMIDE COMPOUNDS USEFUL AS HISTONE DEACETYLASE INHIBITORS
摘要 <p>The invention concerns benzamide compounds of formula (I), wherein R1 is a C-linked pyrazole ring, which is optionally substituted by one or more groups selected from C1-4alkyl, C3-4cycloalkyl, C1-4alkoxy and C3-4cycloalkoxy; or a pharmaceutically acceptable salt or pro-drug form thereof. The invention also concerns processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumors or other proliferative conditions, which are sensitive to the inhibition of histone deacetylase (HDAC).</p>
申请公布号 SI1954690(T1) 申请公布日期 2013.08.30
申请号 SI20060031627T 申请日期 2006.10.17
申请人 ASTRAZENECA AB 发明人 ANDREWS DAVID MICHAEL;STOKES ELAINE SOPHIE ELIZABETH;TURNER ANDREW;WARING MICHAEL JAMES
分类号 C07D401/06 主分类号 C07D401/06
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