发明名称 |
METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEIN AND PEPTIDE THERAPEUTIC AGENTS |
摘要 |
The present invention provides a pharmaceutical composition formulated for oral delivery, comprising a particulate non-covalently associated mixture of pharmacologically inert silica nanoparticles having a hydrophobic surface, a polysaccharide, and a biologically active protein or peptide suspended in an oil. The present invention further provides methods of manufacturing same and therapeutic methods utilizing same for oral delivery of a therapeutic protein or peptide. |
申请公布号 |
EA018461(B1) |
申请公布日期 |
2013.08.30 |
申请号 |
EA20100070827 |
申请日期 |
2009.01.08 |
申请人 |
OSHADI DRUG ADMINISTRATION LTD. |
发明人 |
VOL ALEXANDER;GRIBOVA ORNA |
分类号 |
A61K9/16;A61K9/50;A61K9/54 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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