| 摘要 |
The invention relates to products of the formula (I) in which X-Y is NH-C(S), N=C-NRR, N=C-SR, N=C-R or N=C-OR; R and Rare H or optionally substituted cycloalkyl, alkyl, heterocycloalkyl, aryl or heteroaryl; Ris H, Hal or alkyl; Ris H, Hal, OH, alkyl or alkoxy; Ris H, Hal, CN, CFor alkyl; Ris essentially H, Hal, OH, NRR, cycloalkyl, alkyl, alkoxy, heterocycloalkyl, aryl or heteroaryl, optionally substituted; Ris H, Hal, OH, NH(alk), N(alk), alkyl or alkoxy; with Rand Rbeing such that one is H or optionally substituted alk, while the other is H or optionally substituted cycloalkyl, alkyl, heterocycloalkyl, heteroaryl or aryl; or with Rand Rforming together with N an optionally substituted cyclic radical optionally containing O, S or N. The invention also relates to isomers and salts thereof used as drugs and essentially as protein kinase inhibitors, in particular CDC7. |
