SYNTHESIS OF PURINE NUCLEOSIDES

摘要

ABSTRACT - 593647 The disclosure relates to process for preparing phosphoramidate prodrugs or cyclic phosphate prodrugs of nucleoside derivatives, which is a compound represented by formula (II), its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, wherein R7 is C1-6 alkyl or C3-6 cycloalkyl and R8 is -O(C1-6 alkyl) or -O(C3-6 cycloalkyl). These compounds are suitable for the treatment of a hepatitis C virus infection.