IMPLANTABLE DEVICES FOR TREATING HIV

摘要

Abstract 593950 The present disclosure relates to an implantable device for treating HIV infection. Disclosed is an implantable device comprising a biocompatible, biodegradable polymer mixed with TMC278 and with one or more release-enhancing agents selected from the group consisting of poloxamers, polysorbates, and a combination of dimethyl sulfoxide (DMSO) and poly( vinyl pyrrolidone)(PVP).