METHOD FOR PROMOTING NEURITE OUTGROWTH AND SURVIVAL OF DOPAMINERGIC NEURON

摘要

PROBLEM TO BE SOLVED: To provide methods for promoting neurite outgrowth and survival of dopaminergic neurons.SOLUTION: The invention relates generally to methods for promoting regeneration, outgrowth and survival of dopaminergic neurons comprising bringing the dopaminergic neurons into contact with an effective amount of a composition comprising an Sp35 antagonist. Additionally, the invention is related generally to methods for treating various diseases, disorders or injuries associated with dopaminergic neuronal degeneration or death by administration of an Sp35 antagonist.