| 发明名称 |
1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS |
| 摘要 |
<p>The present invention relates to the 1 H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3ß) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.</p> |
| 申请公布号 |
CA2860250(A1) |
申请公布日期 |
2013.08.29 |
| 申请号 |
CA20132860250 |
申请日期 |
2013.02.07 |
| 申请人 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. |
发明人 |
ALISI, MARIA ALESSANDRA;CAZZOLLA, NICOLA;DRAGONE, PATRIZIA;FURLOTTI, GUIDO;MAUGERI, CATERINA;OMBRATO, ROSELLA;MANCINI, FRANCESCA |
| 分类号 |
C07D401/12;A61K31/454;A61K31/4545;A61P3/00;A61P25/00;A61P29/00;A61P35/00;C07D401/14;C07D405/14 |
主分类号 |
C07D401/12 |
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