发明名称 |
MESENCHYMAL STEM CELLS FOR IN VITRO MODELING AND CELL-BASED THERAPY OF HUMAN DISEASES AND BANKS THEREOF |
摘要 |
A method of qualifying a mesenchymal stem cell (MSC) population is disclosed. The method comprises: (a) ex vivo differentiating a population of mesenchymal stem cells originating from the subject towards a first lineage-specific cell, the first lineage-specific cell being associated with a brain disease; (b) ex vivo differentiating a population of mesenchymal stem cells originating from a healthy subject towards the first lineage-specific cell; (c) comparing an effect of the first lineage specific cell derived from the subject with an effect of the first lineage specific cell derived from the healthy subject on a second lineage specific cell associated with the brain disease, wherein a difference in the effect above or below a predetermined level is indicative of a qualification of a mesenchymal stem cell population. |
申请公布号 |
WO2013124815(A2) |
申请公布日期 |
2013.08.29 |
申请号 |
WO2013IB51428 |
申请日期 |
2013.02.21 |
申请人 |
BRAINSTEM BIOTEC LTD. |
发明人 |
BRODIE, CHAYA;SLAVIN, SHIMON |
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