发明名称 |
MODIFIED MICROBIAL TOXIN RECEPTOR FOR DELIVERING AGENTS INTO CELLS |
摘要 |
We described a novel system of targeted cell therapy with a protein toxin, such as anthrax toxin, that has been modified to re-direct it to a desired cell target instead of its natural cell target. The system can be used for, e.g., targeted killing of undesired cells in a population of cells, such as cancer or overly active immune system cells. |
申请公布号 |
CA2865243(A1) |
申请公布日期 |
2013.08.29 |
申请号 |
CA20132865243 |
申请日期 |
2013.02.22 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
MECHALY, ADVA;MCCLUSKEY, ANDREW J.;COLLIER, R. JOHN |
分类号 |
C07K19/00;A61K47/42;C07K14/705 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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