发明名称 SIRTUIN INDUCER, TISSUE REPAIRING AGENT, HEPATOCYTE GROWTH FACTOR INDUCER, TISSUE HOMEOSTASIS MAINTENANCE AGENT, AND TLR4 AGONIST, HAVING HYALURONIC ACID FRAGMENT AS ACTIVE INGREDIENT
摘要 Provided are a TLR4 agent, a tissue homeostasis agent, a hepatocyte growth factor inducer, a tissue repairing agent, and a sirtuin inducer using hyaluronic acid fragments. Hyaluronic acid fragments selected from sizes of 2-20 sugar units, inclusive, or a pharmaceutically acceptable salt or solvate thereof, are used as the active ingredients of a TLR4 agent, a tissue homeostasis agent, a hepatocyte growth factor inducer, a tissue repairing agent, and a sirtuin inducer. The hyaluronic acid fragments are preferably hyaluronic acid fragments selected from sizes of 3-10 sugar units, inclusive, and more preferably are hyaluronic acid fragments of 3 or 4 sugar units.
申请公布号 CA2871993(A1) 申请公布日期 2013.08.29
申请号 CA20132871993 申请日期 2013.02.21
申请人 HYALURONAN RESEARCH INSTITUTE, INC. 发明人 ASARI, AKIRA;CODEE, JEROEN
分类号 A61K31/728;A23L1/30;A61K8/60;A61K8/73;A61K31/7016;A61K31/702;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P11/00;A61P13/12;A61P17/16;A61P19/02;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P43/00;A61Q19/08 主分类号 A61K31/728
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