发明名称 |
AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES |
摘要 |
Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.
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申请公布号 |
US2013225580(A1) |
申请公布日期 |
2013.08.29 |
申请号 |
US201313781412 |
申请日期 |
2013.02.28 |
申请人 |
CHEMOCENTRYX, INC.;CHEMOCENTRYX, INC. |
发明人 |
CHEN XI;FAN JUNFA;FAN PINGCHEN;KRASINSKI ANTONI;LI LIANFA;LUI REBECCA M.;MCMAHON JEFFREY P.;POWERS JAY P.;ZENG YIBIN;ZHANG PENGLIE |
分类号 |
C07D405/14;A61K31/415;A61K31/4709;A61K31/4725;A61K31/502;A61K31/517;A61K31/5377;A61K45/06;C07D231/42;C07D401/04;C07D401/10;C07D403/10 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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