发明名称 AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES
摘要 Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.
申请公布号 US2013225580(A1) 申请公布日期 2013.08.29
申请号 US201313781412 申请日期 2013.02.28
申请人 CHEMOCENTRYX, INC.;CHEMOCENTRYX, INC. 发明人 CHEN XI;FAN JUNFA;FAN PINGCHEN;KRASINSKI ANTONI;LI LIANFA;LUI REBECCA M.;MCMAHON JEFFREY P.;POWERS JAY P.;ZENG YIBIN;ZHANG PENGLIE
分类号 C07D405/14;A61K31/415;A61K31/4709;A61K31/4725;A61K31/502;A61K31/517;A61K31/5377;A61K45/06;C07D231/42;C07D401/04;C07D401/10;C07D403/10 主分类号 C07D405/14
代理机构 代理人
主权项
地址