摘要 |
The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated. |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
SIDDIQUI, M. ARSHAD;NAN, YANG;PATEL, MEHUL, F.;REDDY, PANDURANGA ADULLA P.;MANSOOR, UMAR FARUK;MENG, ZHAOYANG;VITHARANA, LALANTHI DILRUKSHI;ZHAO, LIANYUN;MANDAL, AMIT, K.;LIU, DUAN;TANG, SHUYI;MCRINER, ANDREW;BELANGER, DAVID, B.;CURRAN, PATRICK, J.;DAI, CHAOYANG;ANGELES, ANGIE, R.;YANG, LIPING;DANIELS, MATTHEW HERSH |