ENHANCEMENT OF SKELETAL MUSCLE STEM CELL ENGRAFMENT BY DUAL DELIVERY OF VEGF AND IGF-1

摘要

An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ECM component; (b) a combination of growth factors such as VEGF and IGF; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration and repair over an extended period of time.