摘要 |
<p>A compound of the formula:
wherein
X is -N=, -CH=, or the like;
W is -CH 2 - or the like;
U is -S- or the like;
R 1 and R 2 are each independently hydrogen, halogen, optionally substituted lower alkyl, or the like;
R 3 is hydrogen or the like;
each R 4 is independently hydrogen, halogen, or the like;
m is an integer from 0 to 2;
Q is a single bond, or the like;
G is -C(=O)-, or the like;
D is a single bond, -NH-, or the like; and
E is a cyclic quaternary ammonium group,
or an ester, a protected compound at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof.</p> |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
HISAKAWA, SHINYA;HASEGAWA, YASUSHI;AOKI, TOSHIAKI;KUSANO, HIROKI;SANO, MASAYUKI;SATO, JUN;YAMAWAKI, KENJI |