发明名称 NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE
摘要 [Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases. [Means of solving the problem] A compound of Formula (I): (where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl group which is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is O, S, -NR 7 -; and R 1 to R 7 are specific groups), a salt of the compound, or a solvate of the salt or the compound.
申请公布号 ZA201203416(B) 申请公布日期 2013.08.28
申请号 ZA20120003416 申请日期 2012.05.10
申请人 MOCHIDA PHARMACEUTICALS CO LTD 发明人 OKANO AKIHIRO;KOSUGA NAOTO;OHKOUCHI MUNETAKA;HOTTA DAIDO;MAKABE MUNEYOSHI
分类号 C07D;A61K;A61P 主分类号 C07D
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