| 发明名称 |
N-HETEROCYCLIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS |
| 摘要 |
<p>The present invention is directed to compounds of formula (I) (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.</p> |
| 申请公布号 |
EP2312949(B1) |
申请公布日期 |
2013.08.28 |
| 申请号 |
EP20090807060 |
申请日期 |
2009.07.31 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
KUDUK, SCOTT, D.;DI MARCO, CHRISTINA, NG |
| 分类号 |
A61K31/47;A61K31/4709;A61P25/00;C07D215/56;C07D401/10;C07D413/10;C07D417/10;C07D471/04 |
主分类号 |
A61K31/47 |
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