| 摘要 |
A preparation method of chromenone derivatives using radiation is provided. The preparation method exposes commercially-available silybin in reaction solvent to radiation, to thereby concurrently obtain both dehydrosilybin and apigenin compounds, which are chromenone compounds, in a simple reaction step and with high yield. Because the compounds are prepared at economic cost, the preparation method can be advantageously used particularly for the purpose of mass production. Further, in consideration of good cancer cell viability suppression effect thereof, dehydrosilybin and apigenin prepared according to the preparation method can be advantageously used as a pharmaceutical composition for prevention and treatment of cancer. |
