System and method for dynamically configurable deep brain stimulation

摘要

A DBS system and method for predicting future neurological activity in a subject and administering a corrective electrical stimulation signal to prevent anticipated pathological neuronal activity. The DBS system includes an implantable electrode configured to both record neuronal activity from a target brain area in a subject and administer the corrective electric stimulation signal to the target area. The DBS system also includes a controller configured to determine the characteristics of the corrective electrical stimulation signal based on point process models of healthy and pathological neuronal activity in the target area.