发明名称 |
ANTITUBERCULOUS THERAPEUTIC AGENT BASED ON 4-THIOUREIDEIMINOMETHYLPYRIDINIUM PERCHLORATE, METHOD FOR PRODUCING THEREOF AND METHOD FOR TREATMENT |
摘要 |
This invention relates to the field of chemical-pharmaceutical industry, specifically a new tuberculosis treatment that contains, as an active ingredient, 4-thioureido-iminomethylpyridinium perchlorate at a therapeutically effective and safe level and pharmaceutically acceptable excipients. In addition, this treatment relates to a method of the preparation of the new drug, providing a high yield of the new treatment. The new treatment has a higher tuberculostatic activity (200 times as high) and lower toxicity (2.4 times as low), as compared to a prototype drug, and is stable during long-term storage. This medicament may be used for treating and preventing all forms of pulmonary and extrapulmonary TB by using the new treatment in combination with other TB drugs. |
申请公布号 |
UA102970(C2) |
申请公布日期 |
2013.08.27 |
申请号 |
UA20120011533 |
申请日期 |
2011.04.12 |
申请人 |
JOINT STOCK COMPANY "PHARMASYNTEZ" |
发明人 |
GUSHCHIN, ALEKSANDER SERGEEVICH;VINOGRADOVA, TATIANA IVANOVNA;YABLONSKIY, PETR KAZIMIROVICH;BANYUNIN, GENNADY ANDREEVICH;ZABOLOTNYH, NATALYA VYACHESLAVOVNA;VASILIEVA, SVETLANA NIKOLAEVNA;MALIGIN, ALEXEY VLADIMIROVICH |
分类号 |
A61K31/4409;A61K31/145;A61P31/06 |
主分类号 |
A61K31/4409 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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