发明名称 |
Salts of (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-trifluoromethyl-5,6,7,8-tetrahydroimidazo[1,5-a] pyrazine-1-carboxylic acid, preparation method and medical use thereof |
摘要 |
Pharmaceutically acceptable salts of (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-formic acid, their preparation methods, compositions containing the said pharmaceutical salts and their use as medicaments, especially as dipeptidyl peptidase IV (DPP-IV) inhibitors are disclosed. Of the many acceptable salts, one example is the following.
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申请公布号 |
US8518946(B2) |
申请公布日期 |
2013.08.27 |
申请号 |
US201113225050 |
申请日期 |
2011.09.02 |
申请人 |
TANG PENG CHO;SUN PIAOYANG;YANG FANGLONG;LIANG JINDONG;SHEN GUANGYUAN;WANG YANG;FAN JIANG;JIANGSU HENGRUI MEDICINE CO., LTD.;SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. |
发明人 |
TANG PENG CHO;SUN PIAOYANG;YANG FANGLONG;LIANG JINDONG;SHEN GUANGYUAN;WANG YANG;FAN JIANG |
分类号 |
A61K31/495 |
主分类号 |
A61K31/495 |
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