<p>Method for preparing a practically anhydrous tiotropium bromide micronizate (A) comprises comminuting crystalline tiotropium bromide monohydrate (I) in a gas-jet mill in which the particles are comminuted in a fluidized powder bed. An independent claim is included for (A) produced by the new method. ACTIVITY : Antiasthmatic. No details of tests for antiasthmatic activity are given. MECHANISM OF ACTION : Anticholinergic.</p>
申请公布号
DK1962960(T3)
申请公布日期
2013.08.26
申请号
DK20060830454T
申请日期
2006.12.07
申请人
BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG
发明人
RASENACK, NOBERT;WALZ, MICHAEL;GRAEBNER, HAGEN;TRUNK, MICHAEL