发明名称 |
METHODS OF ISOTHERMAL AMPLIFICATION USING BLOCKED PRIMERS |
摘要 |
<p>Methods for rapidly detecting clinically relevant mutations in the infectious genome of an agent are disclosed. The methods include use of a novel target and temperature dependent RNase H mediated cleavage of blocked DNA primers to initiate isothermal helicase-dependent amplification of a target sequence such as a sequence in the the rpoB gene.</p> |
申请公布号 |
CA2881200(A1) |
申请公布日期 |
2013.08.22 |
申请号 |
CA20132881200 |
申请日期 |
2013.02.14 |
申请人 |
GREAT BASIN SCIENTIFIC |
发明人 |
JENISON, ROBERT D.;HICKE, BRIAN;WEST, MADELINE |
分类号 |
C12P19/34;C12Q1/68 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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