发明名称 |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors |
摘要 |
The present invention provides protein kinase inhibitors comprising imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine compounds of the following structure (I) and (II), or a stereoisomer, prodrug or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer and other Pim kinase-associated conditions are also disclosed. |
申请公布号 |
AU2007316417(B2) |
申请公布日期 |
2013.08.22 |
申请号 |
AU20070316417 |
申请日期 |
2007.11.06 |
申请人 |
TOLERO PHARMACEUTICALS, INC. |
发明人 |
VANKAYALAPATI, HARIPRASAD;BEARSS, DAVID J.;LIU, XIAO-HUI;XU, YONG |
分类号 |
C07D487/04;A61K31/5025;A61K31/519;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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