Compounds, composition, methods, targets for cancer therapy

摘要

This invention describes methods and pharmaceutical compositions for combinational cancer treatments that are capable of blocking cancer cell trans-plasma membrane electron transfer and respiration in combination with inhibiting cancer cell hypoxia responses to induce cell death. It also 5 identified genes as target for anti-cancer drug development and enhancement of the chemotherapeutic drug effect for the treatment of cancer. This invention points to a novel method and principle for a new avenue of developing more efficient and low or non-cytotoxic cancer treatment.