发明名称 POLY(AMINO ACID) TARGETING MOIETY
摘要 PROBLEM TO BE SOLVED: To provide a poly(amino acid) targeting moiety.SOLUTION: The invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method for developing nanoparticles with desired properties. In one set of embodiments, the method includes a step of producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries.
申请公布号 JP2013163696(A) 申请公布日期 2013.08.22
申请号 JP20130110581 申请日期 2013.05.27
申请人 MASSACHUSETTS INST OF TECHNOLOGY <MIT>;BRIGHAM & WOMEN'S HOSPITAL INC 发明人 ALEXIS FRANK;ZHANG LIANGFANG;RADOVIC-MORENO ALEKSANDAR F;GU FRANK X;BASTO PAMELA;LEVY-NISSENBAUM ETGAR;CHAN JULIANA;LANGER ROBERT S;FAROKHZAD OMID C
分类号 A61K9/51;A61K31/136;A61K31/337;A61K39/395;A61K45/00;A61K47/24;A61K47/32;A61K47/34;A61K47/42;A61P9/08;A61P9/14;A61P35/00;C07C323/58;C07F9/165;C07K7/06 主分类号 A61K9/51
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